Smart pills
Pills are supposed to be for the sick. But some are
being used by perfectly healthy people. Are we heading for a future
of 'cosmetic pharmacology'?
If you could take a drug to boost your brainpower, would you?
This is closer to reality than you might think. New mind-enhancing
drugs are already on pharmacy shelves, and many people are finding
the promise of sharper thinking through chemistry highly
seductive.
Drugs to enhance performance are nothing new. Long-haul lorry
drivers and aircraft pilots are known to pop amphetamines to stay
alert, and university students down caffeine tablets to ward off
drowsiness during all-nighters. But these stimulants work by
revving up the entire nervous system and the effect is only
temporary.
A new generation of cognitive enhancers can improve mental
functions in a lasting way. These drugs result from the drive to
develop treatments for Alzheimer's disease, Parkinson's disease and
other conditions.
Three brain-boosting medications are on the market, available on
prescription. Modafinil (marketed under the name Provigil) is a
treatment for narcolepsy and other sleep disorders that is proving
popular among healthy people who want to enhance their mental
prowess.
Another is methylphenidate, better known as Ritalin, the drug
used to treat attention deficit hyperactivity disorder (ADHD). And
finally donepezil, prescribed for patients with Alzheimer's.
None of these drugs is approved for use in healthy individuals,
but a growing number of people are taking them to gain a mental
edge. Modafinil, when given to adults playing games specially
designed to test mental skills, has been shown to increase
cognitive agility, by increasing alertness and the ability to
concentrate on a task.
Students will no doubt find smart drugs tempting. Indeed, it has
been found that some parents use the Ritalin prescribed to their
children, and some academics take these drugs regularly to enhance
their memory and concentration. Some users persuade a doctor to
prescribe it; others get it illegally over the internet.
Arguments over smart drugs are raging. If a drug can improve an
individual's performance, and they do not experience side effects,
some argue, it cannot be such a bad thing. What is the difference
between a can of caffeine-containing Red Bull and a hike from
modafinil?
But where will it all stop? Ambitious parents may start giving
mind-enhancing pills to their children. People go to all sorts of
lengths to gain an educational advantage and eventually success
might be dependent on access to these mind-improving drugs. No
major studies have been conducted on the long-term effects. Some
neuroscientists fear that, over time, these memory-enhancing pills
may end up causing people to store too much detail, cluttering the
brain.
Wipe away the pain
So what about the flip side: a drug to erase bad memories? It
may have failed Jim Carrey in 'Eternal Sunshine of the Spotless
Mind', but neuroscientists have now discovered an amnesia drug that
can dull the pain of traumatic events. The drug, propranolol, was
originally used to treat high blood pressure and heart disease.
Doctors noticed that patients given the drug suffered fewer signs
of stress when recalling a trauma.
Scientists found that the drug can disrupt the way memories are
stored. This ability could be invaluable in treating trauma victims
to prevent associated stress disorders. The research has also
triggered suggestions that licensing these memory-blocking drugs
may lead to healthy people using them to erase memories of awkward
conversations, embarrassing blunders and any feelings for that
devious ex-girlfriend.
It may seem tempting to use a drug to prevent a painful
experience becoming an unwanted memory. But how would that affect
our development as individuals? Bad experiences help make us what
we are. We learn from them. They help us avoid repeating
mistakes.
And there are other uses that may make us uncomfortable. The
military is interested in modafinil as a drug to maintain combat
alertness. A drug such as propanolol could be used to protect
soldiers from the horrors of war. That could be considered a good
thing - post-traumatic stress disorder is common in soldiers. But
the notion of troops unaffected by their experience makes many feel
uneasy.